FNIPday - NEUROIMAGING & PHOTONICS

A custom real-time DLS setup to monitor nanopulse plasma-driven structural transitions in EAK16IV peptides

Not scheduled

40m

Sala Colonne - Palazzo Bo

Poster P12 Poster Session

Speaker

Mr Alessandro Andreetto (Department of Physics and Astronomy, University of Padova, Via Marzolo 8, 35131, Italy)

Description

Cold atmospheric plasma (CAPs) are a promising tool for many applications ranging from materials processes to plasma medicine [1]. We investigated how a nanopulse APPJs influences the self-assembly of EAK16-IV at varying salt concentrations. Atomic Force Microscopy revealed that the nanopulse plasma induces ribbon-like nanostructures, compared to spherical shapes under control conditions at physiological pH (7.0). A custom Dynamic Light Scattering setup showed that higher salt concentrations led to particle clustering rather than individual growth, with clusters migrating collectively due to enhanced ionic interactions, allowing salt concentration optimisation. Future work will integrate real-time DLS with nanopulse treatment to monitor peptide structural evolution upon plasma exposure [1].

[1] Krewing et all., Plasma Chem Plasma Process 40, 685 (2020)