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5/23/26, 12:00โฏPMComputational and data-driven approaches in microfluidicsPoster
Microfluidic device development often demands labour-intensive fabrication and complex control setups. Here, we introduce a fully 3D printed pneumatic valving platform that combines simulation-driven design, flexible filament, and direct-print integration to enable rapid, assembly-free prototyping. Using fused deposition modeling (FDM) with flexible thermoplastic polyurethane (TPU), we...
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5/23/26, 12:20โฏPMComputational and data-driven approaches in microfluidicsPoster
Compound droplets have attracted significant attention in recent years due to their wide-ranging applications in targeted drug delivery, nanoparticle synthesis, encapsulation technologies, and biomedical diagnostics. Their ability to encapsulate multiple functional materials within a single droplet enables controlled release, enhanced stability, and multifunctional performance, making them...
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5/23/26, 12:40โฏPMComputational and data-driven approaches in microfluidicsPoster
The analysis of biological and environmental samples is of fundamental importance for human health and safety. In particular, the ability to extract target-sized particles from complex suspensions is highly relevant across several fields, ranging from environmental monitoring to biomedical applications (Caragnano et al., 2025). Especially when only limited sample volumes are available, the...
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5/23/26, 1:00โฏPMComputational and data-driven approaches in microfluidicsPoster
The precise characterization of capillary jet breakup and droplet formation is fundamental to numerous applications, from inkjet printing to biochemical assays. While high-speed imaging provides detailed temporal data on these fast-evolving phenomena, manual analysis remains a significant bottleneck, particularly for large datasets involving complex fluid behaviors. This study presents an...
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5/23/26, 1:20โฏPMAnalytical and chemical applicationsPoster
Sodium nitroprusside is an FDA-approved medication used during hypertensive crises. When this drug reacts with metallic salts, it forms metalโnitroprusside complexes, which have good electrochemical and photocatalytic activities. Recently these complexes have been studied for cancer treatment. Under acidic conditions โ such as those found into the tumor cells โ metal-nitroprusside materials...
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5/23/26, 1:40โฏPMAnalytical and chemical applicationsPoster
The issue of microplastics (MPs) pollution is becoming increasingly significant for the environment and health due to the uncontrolled release of plastic waste. It is also a health concern, particularly when considering their release in pharmaceutical liquid products. This serious contamination, which has become a concern since the last few years, demands the development of new methodologies...
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5/23/26, 2:00โฏPMNanofluidics and molecular transportPoster
Interfacial thermal resistance, commonly expressed through the effective Kapitza length ใ(Lใ_(k-eff)) , fundamentally constrains heat transport at the nanoscale and sets performance limits for emerging thermal management and energy-conversion technologies. Although surface chemistry and temperature effects have been extensively examined for idealized solidโliquid interfaces, how wettability,...
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5/23/26, 2:20โฏPMNanofluidics and molecular transportPoster
The development of sensitive point-of-care (POC) diagnostics is often hindered by low target analyte concentrations and matrix interference. This work presents a comprehensive microfluidic framework leveraging Ion Concentration Polarization (ICP) to overcome these challenges through two primary pathways: integrated on-chip and off-chip preconcentration of biomolecules for several biosensing...
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5/23/26, 2:40โฏPMCells, microbes, and extracellular vesicles manipulationPoster
Light is a key environmental cue shaping microbial dynamics in the ocean, yet its role in regulating bacterial motility remains poorly understood. As part of a study exploring light-mediated microbial interactions within the phycosphere, we investigated the behavioral response of the marine bacterium Alteromonas macleodii to controlled illumination. Using high-speed video microscopy and...
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5/23/26, 3:00โฏPMCells, microbes, and extracellular vesicles manipulationPoster
This study investigates the effects of cholesterol and microparticles on the structural and mechanical properties of DPPC monolayers, which serve as models for lung surfactants at the air-water interface. Using
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compression isotherms, fluorescence imaging, and interfacial rheology, we show that cholesterol incorporation increases the elasticity of DPPC monolayers by inserting its steroid rings... -
5/23/26, 3:20โฏPMCells, microbes, and extracellular vesicles manipulationPoster
The bacterial flagellar motor (BFM) is the macromolecular rotary machinery responsible for bacterial motility through flagellar rotation. Its dynamics are tightly regulated by environmental sensing mechanisms, including multiple taxis pathways [1]. In magnetotactic bacteria (MTB), both chemical and magnetic cues modulate BFM behavior, enabling navigation in complex environments [2]. This work...
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5/23/26, 3:40โฏPMCells, microbes, and extracellular vesicles manipulationPoster
The ocular delivery of therapeutic agents is generally restricted by the eye's natural barriers, necessitating advanced drug delivery systems. Novel drug-delivery technologies, such as liposomes, are raising attention as potential ophthalmic drug delivery systems, due to their capacity to encapsulate and efficiently deliver also highly lipophilic drugs. In this respect, the present study...
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Ankur Deep Bordoloi (CNRS, Aix Marseille University, Marseille, France)5/23/26, 4:00โฏPMCells, microbes, and extracellular vesicles manipulationPoster
Cancer metastasis critically depends on cell migration through physically confined and flow-driven microenvironments. In this study, we investigate breast cancer cell migration in a microfluidic platform that mimics a heterogeneous, collagen-coated constriction network under interstitial flow. Migration of MDA-MB-231 cells in a two-dimensional network of micron-scale pores was compared with...
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5/23/26, 4:20โฏPMFlow, wetting, and transport phenomenaPoster
Red blood cells (RBCs) can display a wide range of behaviours, depending on the capillary number (Ca, ratio of viscous to surface tension forces) and confinement parameters. However, real RBCs are not easily available, biodegradable and highly variable. Since they do not contain a nucleus, we propose to model RBCs as membrane-encapsulated liquid droplets, which gives flexibility to tune their...
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5/23/26, 4:40โฏPMFlow, wetting, and transport phenomenaPoster
Fluid-structure interactions are commonly used in the development of microfluidic analogues of microelectronic devices. Examples that exist already in the literature include microfluidic diodes, transistors, and capacitors. In this talk, we theoretically and experimentally explore a microfluidic fuse, a device which prevents fluid flow above a determined critical flow rate. These devices...
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5/23/26, 5:00โฏPMFlow, wetting, and transport phenomenaPoster
Despite the extensive investigations of jet formation and breakup in co-flowing microfluidics, far less attention has been given to how a microfluidic jet interacts with an interface between two immiscible fluids. Here we experimentally study the interaction between a microfluidic jet and a water-silicone oil interface in a nested, co-flowing capillary microchannel. An inertial jet of water is...
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5/23/26, 5:20โฏPMFlow, wetting, and transport phenomenaPoster
The controlled and reproducible splitting of liquid droplets is a key function in many fields and for microfluidic applications. In recent years, various strategies have been used to achieve this task. In this work, we present an optofluidic technique based on an engineered surface composed by coating aย z-cut iron-doped lithium niobate (Fe:LiNbO3) crystal with a lubricant-infused layer...
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5/23/26, 5:40โฏPMFlow, wetting, and transport phenomenaPoster
Proton exchange membrane fuel cells (PEMFCs) are subjected, during their lifetime, to freeze/thaw cycles of water produced in the catalytic layers and remaining after cell shutdown. However, in situ freeze/thaw experiments show that, for the specific types of PEMFCs investigated here, these cycles have no measurable impact on electrochemical performance and suggest that there is no significant...
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5/23/26, 6:00โฏPMFlow, wetting, and transport phenomenaPoster
Capillary-driven flow is a key transport mechanism in many microfluidic systems, graphic products, porous medium, and biological microchannels. Classical models of capillary rise, most notably Washburnโs equation, have been widely used to describe the movement of the liquid column in narrow tubes. This nonlinear second-order ordinary differential equation predicts that the equilibrium height...
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5/23/26, 6:20โฏPMMicrofabrication and device engineeringPoster
Efficient thermal management in compact and sealed systems remains challenging due to the reliance on bulky mechanical pumps and the limited design flexibility of conventional cooling architectures. In this work, we present a pump-less ferrofluidic cooling approach that leverages electro-permanent magnet (EPM) actuation combined with 3D-printed fluidic channels to enable programmable and...
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5/23/26, 6:40โฏPMMicrofabrication and device engineeringPoster
Lipid nanoparticles (LNPs) are a key delivery platform for nucleic acidโbased therapeutics, yet early-stage formulation development is often constrained by high material consumption and limited throughput. We present two complementary technologies addressing these challenges: FLIPS, an automated low-volume particle formulation system optimized for screening, and FDmiX, a scalable microfluidic...
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5/23/26, 7:00โฏPMMicrofabrication and device engineeringPoster
Biological systems in space are exposed to elevated levels of ionising radiation
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and environmental stressors that are difficult to replicate on Earth, yet con-
tinuous in-situ measurements of cellular responses during spaceflight remain
limited. Existing space biology experiments are often constrained by payload
mass, optical complexity, and the need for crew intervention, restricting... -
5/23/26, 7:20โฏPMMicrofabrication and device engineeringPoster
Microbial biofilms present significant challenges in biomedical and industrial contexts, yet their study remains limited by conventional static assays lacking controlled flow conditions and integrated sensing capabilities. In this work, we present a microfabricated biofilm-on-chip platform with integrated electrochemical sensing, designed to enable controlled biofilm cultivation under dynamic...
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Ms Mansi Chandra (Research Scholar (PhD.), Mechanical Engineering, Indian Institute of Technology (BHU) Varanasi, Varanasi, India)5/23/26, 7:40โฏPMMicrofabrication and device engineeringPoster
Although microfluidic lab-on-a-chip devices have revolutionized analytical chemistry and point-of-care diagnostics, their widespread adoption remains limited due to high manufacturing costs and the requirement for specialized fabrication equipment, particularly in resource-constrained settings. This study introduces an innovative, remarkably inexpensive technique for creating paper-based...
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164. Capillary Transport with Rough Walls and Imposed Flux: A Microfluidic Model of Plant Xylem FlowRiddhika Mahalanabis (International Institute of Information Technology Bangalore)5/23/26, 8:00โฏPMFlow, wetting, and transport phenomenaPoster
Capillary-driven transport through narrow conduits is central to microfluidic systems, where surface forces, wall geometry, and externally imposed fluxes jointly determine flow dynamics. In this work, we study water uptake in plants by modelling the xylem as a naturally occurring microfluidic capillary, in which sap rises under capillary action and transpiration-induced suction. Based on this...
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5/23/26, 8:20โฏPMFlow, wetting, and transport phenomenaPoster
Bottom-up synthetic biology aims to construct synthetic cells that recapitulate, understand, and repurpose biological behaviors. Phospholipid giant vesicles (GVs) represent an excellent model for a simplified cell membrane and have been extensively explored in the field. To produce meaningfully biomimetic compartments, GVs need to be cell-sized, unilamellar, and need to encapsulate molecules...
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Kaigang Yang (University of Padova, Physics and Astronomy Department)5/23/26, 8:40โฏPMFlow, wetting, and transport phenomenaPoster
We present the results of an ongoing experimental study about the statics and dynamics of 2D microfluidic crystals confined in a patterned microchannel. More precisely, droplets of uniform size are produced with a T-junction and inserted into a Hele-Shaw cell whose top is patterned with micrometric holes made by standard lithography techniques. A small hole etched in the top wall generates an...
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Ms Despoina Anastasopoulou (Institut de Mรฉcanique des Fluides de Toulouse, UMR 5502 CNRS Institut National Polytechnique de Toulouse, 31400 Toulouse, France and Gรฉosciences Rennes, UMR 6118 CNRS Universitรฉ de Rennes, 35000 Rennes, France)5/23/26, 9:00โฏPMFlow, wetting, and transport phenomenaPoster
Keywords: Hydrodynamic dispersion, Porous media, Quorum sensing, S. aureus, Transport Phenomena
Bacterial environments are inherently dynamic, with fluid flow constantly shaping their physicochemical landscape in non-trivial ways. Quorum sensing (QS) is a key mechanism by which bacteria communicate through the diffusion of QS molecules, termed autoinducers, to cope with these dynamic...
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5/23/26, 9:20โฏPMFlow, wetting, and transport phenomenaPoster
Microfluidic technologies provide powerful tools for manipulating and sorting microscopic objects and play an important role in diagnostics and therapeutic research. Conventional sorting strategies are generally based on physical properties such as density or size, using techniques like centrifugation or microfluidic filtration, while more advanced approaches take advantage of how cells...
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5/23/26, 9:40โฏPMFlow, wetting, and transport phenomenaPoster
Droplet microfluidics has emerged as a powerful platform for biological applications[1], enabling the generation of highly controlled aqueous emulsions dispersed in an oil phase with surfactants. The presence of the droplet-oil interface alters the droplet internal hydrodynamics, leading to modified recirculation patterns and stagnation points compared with monophasic flows. This has important...
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5/23/26, 10:00โฏPMFlow, wetting, and transport phenomenaPoster
Many medically and environmentally relevant pathogens, including viruses and bacteria, exhibit pronounced shape anisotropy, ranging from spherical to elongated geometries. Their removal in pharmaceutical manufacturing and water treatment commonly relies on membrane-assisted depth filtration. Despite its widespread use, a mechanistic understanding of how membrane surface chemistry and particle...
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5/23/26, 10:08โฏPMFlow, wetting, and transport phenomenaPoster
We study microfluidic separation of helical particles with opposite chirality in pressure-driven flow through a cylindrical capillary. Chirality couples the local shear to an axial drift relative to the carrier flow, so left- and right-handed helices acquire equal-magnitude drift in opposite directions, enabling axial separation downstream. We show that adding a small oscillatory modulation to...
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5/23/26, 10:28โฏPMOrgan-on-a-chip and translational modelsPoster
Microfluidic technologies have become indispensable in tissue engineering, primarily due to their ability to manipulate fluids at a scale commensurate with biological microenvironments. However, while biological parameters are frequently prioritized, there remains a critical need to evaluate these platforms from a rigorous engineering perspective to achieve high-throughput optimization and...
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5/23/26, 10:48โฏPMOrgan-on-a-chip and translational modelsPoster
Human neural morphogenesis is a fundamental process of embryonic development that guides the formation of the central nervous system. It originates from an elongated structure called neural tube, which regionalizes and patterns giving rise to distinct neuronal identities spatially organized along its two main axes (antero-posterior and dorso-ventral). Neural tube patterning is regulated by...
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5/23/26, 11:08โฏPMOrgan-on-a-chip and translational modelsPoster
An organoid is a miniature three-dimensional biological structure that mimics certain functions of an organ, though not all. Pluripotent stem cells which can multiply almost indefinitely and differentiate into various types of specialised cells or adult stem cells are used to create organoids. These cells are cultured in vitro under specific conditions promoting their differentiation and...
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5/23/26, 11:28โฏPMOrgan-on-a-chip and translational modelsPoster
Pulmonary surfactant deficiency or dysfunction is associated with several respiratory pathologies, including neonatal respiratory distress syndrome (RDS). In premature infants, lung immaturity limits surfactant production, increasing alveolar surface tension and causing severe breathing difficulties. To treat this condition, surfactant replacement therapy (SRT), based on intratracheal...
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