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Edoardo Maria Mollica (ETH Zürich)5/19/26, 10:00 AMMicrofabrication and device engineeringOral
The aerial surfaces of plants support diverse microbial communities essential to plant function and survival.
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The factors that determine where bacteria first attach and grow on plant leaves remain poorly understood. While microbial colonization of the phyllosphere—leaf, stem, and flower surfaces—has been widely studied, most work has focused on later stages shaped by biological and chemical... -
5/19/26, 10:20 AMMicrofabrication and device engineeringOral
Microbial colonization and biofilm formation drive infection persistence and the spread of antimicrobial resistance, particularly under flow conditions typical of medical and natural environments. Here, we combine spontaneously buckled wrinkled topographies with microfluidic platforms to investigate the adhesion of Pseudomonas aeruginosa and Staphylococcus aureus across shear rates of 0.4–200...
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5/19/26, 10:40 AMCells, microbes, and extracellular vesicles manipulationOral
Microbially induced calcium carbonate precipitation (MICP) often uses ureolytic bacteria, such as Sporosarcina pasteurii (S. pasteurii), which hydrolyze urea and, in the presence of sufficient Ca²⁺, promote calcium carbonate (CaCO₃) precipitation. MICP has been proposed or applied in engineering applications (e.g., soil strengthening, well sealing, hydraulic barriers), but controlling where...
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Pierpaolo Greco (University of Ferrara, Italian Institute of Technology)5/19/26, 11:40 AMAnalytical and chemical applicationsOral
Electrolyte-gated organic transistors (EGOTs) are highly sensitive biosensing platforms whose electrical response is governed by ionic transport and interfacial processes occurring within the electrolyte. In this work, we integrate EGOT devices with a microfluidic cell [1] to systematically investigate how controlled mass transport, diffusion, and interfacial self-assembly influence gate...
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Dr Abdi Mirgissa Kaba (Centre de Recherche Paul Pascal (CRPP), CNRS UMR 5031)5/19/26, 12:00 PMAnalytical and chemical applicationsOral
Directed evolution (DE) is a process of iterative variant generation, screening, and selection to find enzyme variants with improved or specialized functional properties. Advances in droplet-based microfluidics have further expedited DE allowing for rapid screening of large enzyme libraries [1]. Enzyme-expressing genes can be compartmentalized with a fluorogenic substrate inside...
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Mr Johann Savinsky (RWTH Aachen University - AVT.CVT)5/19/26, 12:20 PMAnalytical and chemical applicationsOral
Lipid nanoparticles (LNPs) are central to RNA- and gene-delivery therapeutics, and are increasingly produced using microfluidic mixers. However, LNP sterile filtration during downstream processing remains inherently challenging because LNP dimensions are comparable to the pore size of sterilizing-grade membranes (100 - 200 nm). In this regime, LNP passage and retention are governed by particle...
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Edoardo Massarelli (Politecnico di Milano)5/19/26, 12:40 PMAnalytical and chemical applicationsOral
Light-sheet fluorescence microscopy (LSFM) uses planar illumination to selectively excite a thin optical section of the sample, enabling three-dimensional imaging with reduced photobleaching and phototoxicity [1]. Imaging flow cytometry (IFC) enables high-throughput analysis of large cell populations but is limited to two-dimensional images and relatively low spatial resolution [2]. The...
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